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Hexa-D-arginine TFA
CAS No. 958204-56-3
Hexa-D-arginine TFA ( Furin Inhibitor II TFA )
产品货号. M29859 CAS No. 958204-56-3
Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Hexa-D-arginine TFA
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).
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产品描述Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively). (In Vitro):Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic.(In Vivo):Administration of Hexa-D-arginine (0.1, 1, or 10 nM) to Pseudomonas aeruginosa exotoxin A (PEA)-treated mice (6-week-old FVB and 129/Sv mice) significantly improves their survival rate and also decreases circulating levels of TNF-α.
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同义词Furin Inhibitor II TFA
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通路GPCR/G Protein
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靶点Antibacterial
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受体Ki: 106 nM (Furin), 580 nM (PACE4) and 13.2 μM (PC1)
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研究领域——
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适应症——
化学信息
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CAS Number958204-56-3
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分子量1068.2
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分子式C38H76F3N25O8
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:Arg-Arg-Arg-Arg-Arg-Arg-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Sarac MS, et al. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun. 2002 Dec;70(12):7136-9.
产品手册
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